Diabetes mellitus (DM) is a chronic metabolic disorder caused by an absolute or relative deficiency of insulin, an anabolic hormone, produced by the beta cells of the islets of langerhans located in the pancreas. The absence, destruction, or other loss of these cells re- sults in Diabetes mellitus type 1 (also known as type 1 diabetes, or T1DM; formerly insulin dependent diabe- tes or juvenile diabetes). Autoimmune destruction of insulin-producing beta cells of the pancreas and subse- quent lack of insulin leads to increased blood and urine glucose. Incidence varies from 8 to 17 per 100,000 in Northern Europe and the U.S. with a high of about 35 per 100,000 in Scandinavia to a low of 1 per 100,000 in Japan and China (1).