The rice bran from Kamklaing, a selected local Thai glutinous black rice cultivar (KRB), has
gained interest for its nutraceutical composition and beneficial health effects. The ethanolic
extract of KRB was prepared, analysed by HPLC and investigated for its biological
effects. The results demonstrated that the KRB extracts had a high content of cyanidin-
3-glucoside, caffeic acid and ferulic acid and possessed antioxidation and wound healing
effect. This was associated with increasing migration and collagen synthesis in normal
human dermal fibroblast cells when compared to the controls, MMP-2 and MMP-9 inhibitory
effects in gelatin zymography, and immunomodulation with concentration-dependent
bimodal effects in human monocytes. These results suggest that Kamklaing rice bran is a
promising by-product that contains functional ingredients which may be useful in the
control of skin aging and chronic disease development.
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