Descriptive statistics were calculated for severity and sources of stress. Results indicated that there was a positive recalibration of student perceptions in the areas of transition from preclinical to clinicallevel; ‘‘Performance pressure’’ stressed third year students the most. However, ‘‘Clinical require-ments’’ wasthegreateststressorwith thehighest meanforthefourthandfifth yearstudents. Themean value of total DES score of female students is also statistically higher than that of male students(p< 0.05). The item scores ‘‘Patient treatment’’, ‘‘performance pressure’’ and ‘‘social stressors’’ aresignificantly more stressful in married than in the single study subjects (p< 0.05). The overall findings of this investigation showed that dental students of King Saud University, perceived high levels of stress across all of the five study years with notable significance in the factor domain of ‘‘Workload’’.