Using Bayesian methodology, we
completed one of the first metaanalyses
to use informed priors in
our OR calculations. By incorporating
the results of previous metaanalyses
by Leipzig et al,15,16 our OR
estimates provided a needed update
of the association between falls
and 9 different medication classes.
Wealso estimated frequentist pooled
ORs to measure the association between
falls and medication classes
using research completed since 1996
for comparison to the Bayesian estimates.
Our results extend the current
knowledge on specific medication
classes’ impact on the risk of
falls, while complementing previous
meta-analyses and systematic reviews
that incorporated research
completed before 1996 and 2004,
respectively.15