adequate to produce stabilization via multipoint covalent attachment.Glyoxyl-agarose support immobilizes the enzyme by the richest in Lys residues areas [18,19], and glutaraldehyde-agarose can immobilize by the most reactive amino group (likely the terminal one) or by the most negatively charged areas, or even by hydrophobic inter-actions depending on the conditions of immobilization [17,20].