This lantibiotic producer expressesdifferent immunity systems, which might work synergistically:polymorphism of the peptidoglycan, the lipoprotein MlbQ and theABC-transporter MlbYZ together with the transmembrane proteinMlbJ. It was suggested that both, MlbQ and MlbJYZ, decrease thelantibiotic concentration in proximity to the target lipid II byintercepting the lantibiotic or extruding the membrane-boundlantibiotic to the extracellular space, respectively.