Interventions-Placebo was given for a run in
period of four to six weeks. Metoprolol 100 mg twice
daily or atenolol 25 mg twice daily was then given for
16 weeks. The two drugs were then exchanged and
treatment continued for a further 16 weeks.
End point-Evaluation of effects of treatment
with metoprolol and atenolol on glucose, insulin,
and lipid metabolism and glucose disposal mediated
by insulin.