As presented in Fig. 2 morphine also increased reaction time in 0.3 and 1mg/kg doses (control: 9±0.45 s, morphine 0.3:
10.33±1.28 s, morphine 1: 11.83±1.01 s, P > 0.05) and became statistically significant at 5mg/kg dose (morphine 5: 16.67±2.25 s, P < 0.05).
Morphine at 10 mg/kg avoided mice to show any response against thermal stimulus until cut-off time (30 s; P < 0.01).