In 1933, at the height of the Great Depression, New York City vaudeville actress Ann Darrow has lost her job and is hired by financially troubled filmmaker Carl Denham to star in his new film. Ann signs on when she learns her favorite playwright, Jack Driscoll, is the screenwriter. As their tramp steamer, the SS Venture, makes the lengthy journey to the remote and mysterious Skull Island, Ann and Jack fall in love. Captain Englehorn begins having second thoughts about the voyage, prompted by crew speculation of trouble ahead.