The high prevalence of burnout and the strong correlations between burnout and depression observed in this study is significant because compared to patients with other types of chronic conditions,most patients with depressive symptoms remain in the workforce in addition to absenteeism,increased disability claims and unemployment performance - workers being present at work with reduced performance-is also a significant source of the depression-related burden of disease while depression treatments such as antidepressants and cognitive behavioral therapy have been shown to reduce symptoms and improve work function clinical improvements do not always translate to recovery of productivity. it is possible that burnout could help explain some of the residual work dysfunction and other work-related issues seen in depression. In this context, the variations seen in the degree to which depression relates to the three domains of burnout could be a promising observation. Therefore, clarifying the role of burnout in depression and developing appropriate approaches to treatment could contribute towards a significant unmet need in helping this population