reversal of underlying
disease form cornerstones to successful weaning. Special
emphasis of physiotherapy, nutrition and systemic illness,
and comorbidities associated with COPD needs proactive
management. Given the data supporting the use of NIPPV
postextubation in COPD patients, its use for this indication
should be increased, especially in resource‑limited settings
and extending to situations such as DNI. However,
meticulous monitoring and technically skilled staff make
an integral component of good dedicated NIV unit to
cater to patients with COPD and difficult weaning and
should be established in each tertiary care unit to achieve
best outcomes in such patients.