The beneficial effects of PUFA have been extensively investigated,
however, there are very few studies investigating the effects on human
health with long-term corn oil consumption, particularly on the older
population. This is very important because corn oil is the second leading
vegetable oil consumed in the United States (USDA, 2014). Since U.S.
adults age 65 and older heavily consume this high fat oil, their population
is rapidly increasing and is projected to reach 71million by 2030. The objectives
of the present study are to investigate the long-term health effect
of high volume of corn oil consumption in aging mice and to understand
the relevant mechanisms