Much research has focused on the roles of sociocultural backgrounds such as demographics or acculturation in mental health among immigrants. However, far less is known of the effects of differences in immigrant health status and health behaviors, especially female immigrants in Korea with a relatively short history of migration. Our study advances nursing science on physical and mental health among immigrants by accounting for both the health status and health behavioral aspects related to depression in married female immigrants. Several important areas of investigation have emerged from this study. Future research is warranted to examine factors that influence married female immigrants' health status and health behaviors. Also, to better understand the mechanism by which health and other unexamined indicators affect depression along with possible mediation, a structural equation model approach may be helpful. Building on these studies, effective interventions to promote mental health can be developed and tested.