Atrophy of the brain can be graded according to its size and appearance during autopsy. Grade 1 cerebral atrophy is associated with mild cerebral atrophy, and the changes in the brain are usually minimal and are mostly related to the normal aging process. Grade 2 cerebral atrophy is indicated in moderately severe atrophy of the brain, where moderate widening of the sulci and dilatation of the ventricles are seen. And the changes in Grade 3 mostly corresponds with severe brain atrophy, where there are extreme expansion of the ventricles and dramatic changes in the sulci and gyri.
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