The weaning time is a crucial period in the management of piglets. The risk of development of
post-weaning diarrhoea (PWD) in piglets is high. PWD is the cause of serious economic losses in pig herds. Since
2006, the use of antibiotic growth promoters for prevention of diarrhoeal diseases in piglets has been banned.
This measure also led to the investigation of alternative suitable feed supplements that would be reasonably efficient
in protecting and sustaining animal health and performance. Various natural materials such as probiotics,
prebiotics, organic acids, zinc and plant extracts have been tested as effective alternatives to antibiotics. Recently,
owing to their high adsorption capacity, research efforts have been conducted on the application of natural clays
and clay-based feed supplements. The purpose of this review is to summarize the effect of different alternative
components as growth promoters on the health and performance of weaned and growing piglets