In a series of studies, Yfanti et al. established that daily supplementation
of 500 mg vitamin C and 400 IU of vitamin E does
not impair skeletal muscle or whole-body adaptations to 12 weeks
of endurance training in humans [11–13]. However, human studies
that have reported blunting of skeletal muscle adaptations to endurance
training have used much higher doses of vitamin C of 1 g/
day in combination with vitamin E