5. Conclusion
Methylergometrine and Oxytocin have been used for a long time in markedly different doses and routes of administration with varying success. The use of Methylergometrine as part of AMTSL is associated with statistically significant reduction in duration of third stage of labour, mean blood loss, need for additional uterotonics when compared to Oxytocin but has significant side effects like nausea, vomiting and rise in blood pressure. The choice of drug depends on cost, facilities for storage and refrigeration and assessment of trade-off between benefits and side-effects.