All patients treated with evolocumab experienced LDL-C reductions compared with their individual baseline levels versus 92.9% and 91.3% of ezetimibe-treated patients in the biweekly and monthly groups (Fig. 3). Evolocumab treat- ment in the biweekly and monthly groups led to LDL-C decreases of >50% in 75.7% and 78.7% of patients when evaluated by LDL-C level averaged at weeks 10 and 12 and 76.7% and 72.1% at week 12, respectively.