Changes in the production of secondary metabolites are frequently linked to a number of aspects of the plant’s interaction with its environment. It is therefore no surprise that agronomic factors which influence plant growth and development may also influence the accumulation of some secondary metabolites. The involvement of nitrogen nutrition in influencing plant growth and development and biomass production is universally acknowledged (see review of Fernandes and Rossiello, 1995). Based on this knowledge, it seems entirely appropriate to examine the effects of nitrogen as an interactive factor in driving photosynthesis (via Rubisco content), growth and acting as resource of secondary metabolite production (Wang and Weathers, 2007). It has also be hypothesized that environmental stress, such as nutrient deficiency, via the production of ROS, which are themselves scavenged by dihydroartemisinic acid, produces the stable end product artemisinin (Ferreira, 2007).