Fifteen of the 18 adolescents enrolled at baseline com- pleted the intervention. Two participants dropped out within the first week due to a lack of interest and another participant had a scheduling conflict with work that pre- vented regular attendance of the lifestyle education classes. No significant anthropometric or metabolic dif- ferences were observed between completers and non- completers with the exception of 2-hour glucose, which was lower in noncompleters (90.0 ± 16.0 vs 117.2 ± 4.8, P = 0.047). All subsequent analyses are performed on the 15 participants who completed the intervention unless otherwise noted.
Descriptive, anthropometric, fitness, activity, and nutrition data at baseline and following the intervention are presented in Table 2. Participants attended 91% of the intervention sessions where average heart rates were 150 ± 3.3 beats/min, and although weight did not change, sig- nificant decreases in BMI percentile, BMI z score, and
waist circumference were observed following the inter- vention (all P < 0.05). In addition, cardiorespiratory fitness increased significantly, and although physical activity levels did not change significantly, by the end of the intervention 67% of the participants met the CDC recom- mendations of at least 60 minutes of moderate to vigor- ous physical activity/day (compared to 47% at baseline). Physical inactivity, as measured by total screen time (TV and computer), decreased nearly 47% from 178.6 ± 40.5 to 95.0 ± 26.4 minutes per day (P = 0.01). Significant reductions in reported servings of fat per day were observed, whereas no significant changes in servings of fruits and vegetables were reported (Table 3).
Figure 1A and B presents changes in glucose (A) and insulin (B) concentrations during the OGTT. Although fasting glucose did not change, a trend toward signifi- cance was noted for decreases in fasting insulin (P = 0.06). Significant decreases were observed in 2-hour glucose (10.8%), 2-hour insulin (23.6%), as well as AUC for glucose (16.2%) and insulin (25.5%), all P < 0.01. These improvements correspond to a 29.2% increase in insulin sensitivity as measured by the WBISI (2.4 ± 0.3 to 3.1 ± 0.3; P = 0.01). The only participant who pre- sented with impaired glucose tolerance at baseline (2-hour glucose = 151 mg/dl) was no longer pre-diabetic following the intervention (2-hour glucose = 122 mg/dl).
Fifteen of the 18 adolescents enrolled at baseline com- pleted the intervention. Two participants dropped out within the first week due to a lack of interest and another participant had a scheduling conflict with work that pre- vented regular attendance of the lifestyle education classes. No significant anthropometric or metabolic dif- ferences were observed between completers and non- completers with the exception of 2-hour glucose, which was lower in noncompleters (90.0 ± 16.0 vs 117.2 ± 4.8, P = 0.047). All subsequent analyses are performed on the 15 participants who completed the intervention unless otherwise noted.Descriptive, anthropometric, fitness, activity, and nutrition data at baseline and following the intervention are presented in Table 2. Participants attended 91% of the intervention sessions where average heart rates were 150 ± 3.3 beats/min, and although weight did not change, sig- nificant decreases in BMI percentile, BMI z score, andwaist circumference were observed following the inter- vention (all P < 0.05). In addition, cardiorespiratory fitness increased significantly, and although physical activity levels did not change significantly, by the end of the intervention 67% of the participants met the CDC recom- mendations of at least 60 minutes of moderate to vigor- ous physical activity/day (compared to 47% at baseline). Physical inactivity, as measured by total screen time (TV and computer), decreased nearly 47% from 178.6 ± 40.5 to 95.0 ± 26.4 minutes per day (P = 0.01). Significant reductions in reported servings of fat per day were observed, whereas no significant changes in servings of fruits and vegetables were reported (Table 3).Figure 1A and B presents changes in glucose (A) and insulin (B) concentrations during the OGTT. Although fasting glucose did not change, a trend toward signifi- cance was noted for decreases in fasting insulin (P = 0.06). Significant decreases were observed in 2-hour glucose (10.8%), 2-hour insulin (23.6%), as well as AUC for glucose (16.2%) and insulin (25.5%), all P < 0.01. These improvements correspond to a 29.2% increase in insulin sensitivity as measured by the WBISI (2.4 ± 0.3 to 3.1 ± 0.3; P = 0.01). The only participant who pre- sented with impaired glucose tolerance at baseline (2-hour glucose = 151 mg/dl) was no longer pre-diabetic following the intervention (2-hour glucose = 122 mg/dl).
การแปล กรุณารอสักครู่..
