To assess human data, the presence of a wide range of
vulnerability/susceptibility in exposed individuals should be taken
into account. Age and gender are major modulating factors, together
with nutrition and lifestyles (e.g., smoking, alcohol consumption).
Widespread genetic polymorphisms may also be of importance, as
observed, e.g., for postmenopausal breast cancer risk in association
with PCB exposure
To assess human data, the presence of a wide range ofvulnerability/susceptibility in exposed individuals should be takeninto account. Age and gender are major modulating factors, togetherwith nutrition and lifestyles (e.g., smoking, alcohol consumption).Widespread genetic polymorphisms may also be of importance, asobserved, e.g., for postmenopausal breast cancer risk in associationwith PCB exposure
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