In order to improve the human engineering characteristics of the table tennis wheelchair and promote sport wheelchair, the design of a Table Tennis wheelchair was improved based on the human engineering. With the PRO/E software the table tennis wheelchair three-dimensional model is built and with the CATIA software the three-dimensional human body model is established. At last, in order to validate the human engineering performance of the improved table tennis wheelchair, we carried on the wheelchair man-machine engineering simulation, the operating space analysis of containing, balance analysis and body posture comfort level analysis and appraisal. The results indicated that the improved table tennis wheelchair can satisfy the human engineering request of the security, the efficiency and the comfort.