Orange Juice are can prevent kidney stone disease. According to Dr. Clarita Odvina, assistant professor of internal medicine at the Charles and Jane Pak Center for Mineral Metabolism and Clinical,(2006). In the study, researchers compared the effects of orange juice and lemonade in preventing recurrent kidney stones. Both juices contain comparable citrate levels. Thirteen volunteers, a history of kidney stones, participated in the three-phase study. In random order, the participants drank approximately 13 ounces of either distilled water, orange juice, or lemonade three times a day with meals for one week. The results showed that orange juice increased levels of citrate in the urine and decreased urine acidity, which reduced the risk of kidney stones. But lemonade did not have the same effect. In conclusion Orange juice could potentially play an important role in the management of kidney stone disease.