Amylases are a class of enzymes, which have useful applications in the food, brewing, textile, detergent and pharmaceutical industries. They are mainly employed for starch liquefaction to reduce their viscosity, production of maltose, oligosaccharide mixtures, high fructose syrup and maltotetraose syrup. The use of the submerged culture is advantageous because of the ease of sterilization and process control is easier to engineer in these system. So, the studies of production of amylase by Bacillius sp, in submerged cultures and optimized the cultural conditions were done. The study found that the production of extracellular amylase by Bacillus sp was optimized in a submerged fermentation. The production of the enzyme was maximum at 10 hrs after inoculation. The effect of incubation period, pH of the medium and incubation temperature was optimized. The maximum productions of enzyme were obtained at 35 °C and pH7. Additionally, the experiment found that the production of extracellular amylase by Bacillus sp was optimized in submerged fermentation and solid state fermentation. The optimum conditions for enzyme production were standardized using various parameters such as pH, time and temperature. Amylase produced by Bacillus sp under solid state fermentation as well as submerged fermentation. Solid State Fermentation have been established as a superior technique, economically valuable than the submerged fermentation for the production of enzymes.