1. What's the best DPS combo?
If you don't want to click, then use 8-1-2-3-7 (Note: Although 8+1 should effectively give you 20 clicks per second, it does not account for latency factors which in actuality only gives you around 14-16 clicks per second.)
If you can click more than 5 times per second and don't have Bhaal level 9+, then use 1-2-3-8-7
If you can click more than 5 times per second and have Bhaal level 9+, then use 8-3-7-1-2
Ultimate DPS combo: 8-wait for cooldown-3-8-7-1-2-4-5 or 8-wait for cooldown-3-8-1-7-2-4-5 (This combo effectively allows you to Energize two sets of skills but will require you to wait for the first cooldown)