Elevated levels of D-dimer in blood plasma have been related to severe pathological conditions like pulmonary embolism, septicemia, cirrhosis, carcinoma and sickle cell disease (Raimondi et al., 1993; Wakai et al., 2003). Studies have indicated that D-dimer can be also used as a marker for arterial and venous thrombosis and the prediction of cardiovascular disease. In particular, it has been proposed that blood plasma concentrations over a threshold value of 0.5 mg/mL indicate an increased risk for thrombosis, whereas lower concentrations account for very low risk for a thrombotic episode (Gershlick 1999; Lowe et al., 2001).