In a recent review, almost 100 mixed ‘ternary’ systems containing proteins and polysaccharides in aqueous medium were described as thermodynamically incompatible [19]. This gave an illustration that such a mechanism is a general phenomenon when the biopolymers are in solution. Thermodynamic incompatibility generally arises in conditions when the protein is in the presence of a neutral polysaccharide or of an anionic polysaccharide bearing a charge of the same sign as the protein (close to neutrality); obviously, the main parameters involved in the mechanism are pH and ionic strength.