Long-term tobacco smoking can have adverse effects in nearly every organ of the body and cause a variety of diseases. In the United States, the adverse health effects from cigarette smoking account for more than 480,000 deaths among adults, or nearly one of every five deaths; more deaths are caused each year by tobacco use than by all deaths from human immunodeficiency virus (HIV), illegal drug use, alcohol use, motor vehicle injuries, suicides, and murders combined [1].