The research methodology started from studying of the preliminary study the case study, principles and theories that related with transportation management system, crossdocking, location selection, genetic algorithm and literature review of several methods that used to improve transportation management system, all of these was detailed in the chapter 2. The current state of daily production that started from supplier to customer was created and analyzed by using VSM and 9 logistics activities. The selection of feasible crossdock locations in this research were used simple additive weighting method (SAW) to make a decision by criterions such as customer location and demand. For the next step, GA was become important role, it used to solve VRP with single DC (without crossdocking system) and VRP with crossdocking system. Final approach was an evaluation all alternative solutions by efficiency and economic perspective by using cost-benefits analysis tools; BEP analysis, IRR, and PB. The flow chart of this research designs, tools and methods are shown in figure 3-1 and the details of every step will be described below.