Peptic ulcer disease (PUD) is a disease that results from an imbalance between aggressive factors such as stomach acid and pepsin and mucosa defense barriers (1). Although the need for elective surgery has decreased as a result of advances in medical treatment, 10% of the patients require surgery. The choice of treatment for peptic ulcer perforation (PUP) remains to be surgery. Currently, the most preferred sur¬gical method is simple closure and omental plug. Different techniques are also applied (2-4). Factors that influence the prognosis of PUP are listed as follows: time to hospital presentation, large perforation diameter, age over 60 years, presence of shock, presence of concomitant diseases and localization of the perforation in the stomach (5, 6). Preoperative hemodynamic shock, sepsis and generalized peritonitis are important factors influencing morbidity and mortality (5-8). In this study, we examined the risk fac¬tors affecting morbidity and mortality in PUD