Oral administration of the methanol,aqueous and chloroform extracts of A did not show changes in the general appearance or behavioral pattern of the experimental mice until the end of 14 days.Further,no death was observed in the animals receiving the extract up to a dose of 2000 mg/kg BW,which is about 10 times the minimum effective dose tested.If a test substance has a lethal dose higher than 3 times the minimum effective dose,it can be a good candidate for further studies.Therefore,absence of mortality up to an oral dose of 2000 mg/kg could indicate that the test extracts were safe and this couldexplain the routine use of the plant by the local people for traditional management of malaria.