This paper presents an optical method for real-time monitoring of protein adsorption using porous sili-
con self-supported microcavities as a label-free detection platform. The study combines an experimental
approach with a physical model for the adsorption process. The proposed model agrees well with experi-
mental observations, and provides information about the kinetics of diffusion and adsorption of proteins
within the pores, which will be useful for future experimental designs.