2.7. Determination of particle size distribution and surface charge by dynamic light scattering (DLS)
DLS analysis used a particle analyzer of dynamic light scattering(DLS) (DelsaNanoC, Beckman Coulter) equipped with a laser diode of 658 nm wavelength and 30 mW of power to determine particle size distribution and surface charge on API samples.
The acquisition of data determines the particle size distribution which wasconducted at 25◦C, with an angle of 165◦in a glass cuvette.