In the microorganism, biosynthetic pathway is described,
generally, in three steps: (1) the conversion of acetyl-CoA to 3-
hydroxy-3-methyl glutaryl-CoA (HMG-CoA) and the reaction,
is catalyzed by HMG-CoA synthase. HMG-CoA is then con-
verted into a C
6
compound, mevalonic acid (MVA). MVA is