Introduction Fibromyalgia syndrome (FMS) is a common rheumatologic disorder characterized by pain, fatigue, poor sleep, and muscle/joint stiffness. Most patients with FMS receive care in primary care offices, often from nurse practitioners (NPs). NPs should perceive FMS as a true disorder and feel confident in caring for affected individuals. Purpose The purpose of this research was to explore future nurse practitoners' perceptions of fibromyalgia pain, quality of life (QOL), and their preparedness to treat these issues. Method Based on Heider's Attribution Theory, 21 NP students from two courses at a southeastern university completed a one-time questionnaire. The questionnaire consisted of both quantitative and qualitative questions along with a QOL Model diagram. Findings NP students acknowledged the importance of controlling FMS pain (7.8 on 0-10 scale) and QOL issues (9.43 on 0-10 scale). They lacked confidence in treating FMS pain (3.47 on 0-10 scale), but expressed more certainty in treating QOL issues (6.33 on 0-10 scale). NP students believed FMS pain affects all aspects of QOL. Conclusions NP students acknowledged the importance of FMS pain control and QOL in their practice and felt more confident in caring for QOL issues over FMS pain. Continued skepticism about the disorder exists.