The main difference between the life cycle of P. vivax and Plasmodium falciparum (P. falciparum) is the development of latent forms – known as hypnozoites – in the liver.6 The hypnozoites are not eradicated by standard antimalarials and can awaken days to months to years after the last bout of clinical malaria, in the absence of a mosquito bite, unless drugs specifically targetting the hypnozoite are administered.