For the first time, a simple solvent microextraction method termed vortex-assisted liquid–liquid
microextraction (VADLLME) coupled with gas chromatography–mass spectrometry (GC–MS) has been
developed and used for the analysis of six benzophenone ultraviolet (UV) filters (i.e. benzhydrol,
2,4-dihydroxybenzophenone, benzophenone, 2-hydroxy-4-methoxybenzophenone, ethylhexyl salicylate
and homosalate) in water samples. The most favorable extraction variables in the VADLLME process
were determined. In the extraction procedure, 40 L of tetrachloroethene as extraction solvent were
directly injected into a 15-mL centrifuge tube containing 10 mL of aqueous sample, adjusted to pH 4
for VADLLME. After VADLLME, the extract was evaporated under a gentle nitrogen gas stream and then
reconstituted with N,O-bis-(trimethylsilyl)trifluoroacetamide (BSTFA), thus allowing the target analytes
For the first time, a simple solvent microextraction method termed vortex-assisted liquid–liquidmicroextraction (VADLLME) coupled with gas chromatography–mass spectrometry (GC–MS) has beendeveloped and used for the analysis of six benzophenone ultraviolet (UV) filters (i.e. benzhydrol,2,4-dihydroxybenzophenone, benzophenone, 2-hydroxy-4-methoxybenzophenone, ethylhexyl salicylateand homosalate) in water samples. The most favorable extraction variables in the VADLLME processwere determined. In the extraction procedure, 40 L of tetrachloroethene as extraction solvent weredirectly injected into a 15-mL centrifuge tube containing 10 mL of aqueous sample, adjusted to pH 4for VADLLME. After VADLLME, the extract was evaporated under a gentle nitrogen gas stream and thenreconstituted with N,O-bis-(trimethylsilyl)trifluoroacetamide (BSTFA), thus allowing the target analytes
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