In conclusion, the present study reports the effect of andrographolide
on growth and non-specific immune parameters of L. rohita
fingerlings. The activation of non-specific immune responses in
L. rohita fingerlings could be due to the chemical entity especially
diterpenoid lactone andrographolide that activated non-specific
cell receptors of vital immune cells and stimulated lymphoid cell
colony and tissues. Further significant positive impact on various
growth parameters and higher percentage survival rate of L. rohita
challenged with A. hydrophila infection through 0.10% andrographolide
supplemented diet, strengthened the immunostimulatory
effect.