Cotton is a globally important crop used for both its natural fiber and seed. Fusarium wilt, caused by the
fungus Fusarium oxysporum f. sp. vasinfectum, is a major disease of cotton capable of causing significant
economic loss. The fungus persists in soil as chlamydospores and in association with the roots of susceptible,
resistant and non-cotton hosts as well as in seed. Management of Fusarium wilt is difficult and
most successfully achieved through the use of resistant cultivars and pathogen-free cotton seed. Once
inoculum has been introduced into the field, strategies such as soil solarization and fumigation are
applied to manage inoculum levels. While experimentally successful, these techniques are of limited use
in a commercial setting. Management of Fusarium wilt will continue to rely upon the development of
new resistant cultivars. Additionally, understanding the mechanism of seed colonization and developing
high throughput seed treatment and testing protocols will allow the industry to effectively avoid the
introduction of inoculum.