Clinical trial:We conducted a double-blind randomized placebo-controlled study on 34 women with mild to moderate acne during 60 days.
A noninvasive sampling method was used to collect the skin surface lipids on forehead.
Neutral lipids as well as squalene oxidized were quantified respectively by GC/MS and LC/MS.
We observed highly significant differences between a 3% active formula and placebo on squalene (-28%) and squalene oxidized (-39%).
These results underlined the capacity of the extract to modulate the main inflammatory-related pathways of acne pathogenesis, regulate sebum secretion, improve sebum quality by protecting
bounded fatty acids and limit oxidative alterations of the skin in vivo.
Conclusion: This new cosmetic active ingredient offers a global solution for the management of oily and acne prone skin.