in the last 15 years, much information
related to these nanovesicles has been published (Beveridge
1999; Kuehn and Kesty 2005; Lee et al. 2008; Mashburn-
Warren and Whiteley 2006). Many questions regarding
them remain unanswered, including the molecular mechanism
for the release of OMVs, or the sorting or regulated
compositions of OMVs; in addition, new questions have
arisen. This review will focus on the most recent information
of OMVs from Gram-negative bacteria and the recently
reported findings on vesicles from Gram-positive bacteria.