detailed clinical evaluation or phenotypingto characterize the natural history and etiology of
a disease, or delivery of a psychosocial intervention.The participant’s response to the study intervention may make additional nursing care necessary. These care requirements range from educating the participant about self-monitoring to comprehensive physiologic monitoring and life support in an intensive care unit. Because clinical research is an interdisciplinary
process, the potential contribution of the clinical research nurse includes coordination of research and care as well as management of the interface between study-based care and community services.