not the same:
She seems to wear something different every day.
He's different now that he's been to college.
We're reading a different book this week.
Emily is very/completely/entirely different from her sister.
Emily and her sister are completely different.
There are many different types/kinds of bacteria.
informal used when you think someone or something is unusual or shows bad judgment:
What do I think of your purple shoes? Well, they're certainly different