Ultraviolent (UV) irradiationTwenty-four (24) hours old subculture of L. theobromae was briefly exposed to UV light at 254 nm for1, 2 and 5 min and then incubated for 7 days. After which, solid-state fermentation was carried out by inoculating the media with about 3 mm diameter agar blocks containing the mutated fungal culture and incubated at 27 °C for 21 days. The crude secondary metabolites were extracted using ethyl acetate concentrated at 40 °C under reduced pressure using a rotary vacuum evaporator. The obtained extracts were assayed for their antibacterial activities.