This study focuses on the electrospinning process for
the production of a nanofiber scaffold and assesses the
cell behavior as an indicator for the potential for bone
tissue engineering. Unlike conventional fiber spinning
processes that produce fibers with diameters in the
micron range, electrospinning is capable of producing
fibers in the nanometer diameter range, or nanofibers,
that are typically deposited in the form on non-woven
fabrics. The large diameter reduction from a millimeterscale
fluid jet to a nanoscale solid fiber is due to an
instability, where the jet is stretched by whipping and
bending [9]. Electrospinning is driven by electrostatic
forces and requires only small amounts of polymer. The
latter feature is particularly useful for processing newly
synthesized polymers that are not available in large
quantities. The fiber diameters that are attainable in the
electrospinning process depend on the polymer and
the process conditions. Through judicial choice of the
process parameters, fibers in different diameter ranges
can be obtained. In this particular study, the fibers were