Baboons are closely related to humans phylogenetically,
so the data in this model are significant for
human disease. Adaptability of EBO virulence to rodents
suggested the possibility of circulation in nature
of avirulent, antigenically cross-reactive variants that
might cause mild or subclinical infections in humans
and primates [15]. Therefore, it was important to study
the course of Ebola fever caused by adEBO in baboons.
This information may help to assess the virulence of the
adEBO for higher phylogenetic species.