The effects of a freeze-dried powder of the fruit on serum glucose levels
and lipid parameters of the serum and liver were studied in rats fed
diets supplemented with cholesterol and without cholesterol. For 14 days,
rats were fed the diets either containing the freeze-dried powder at 0.5, 1
or 3% without added dietary cholesterol (experiment 1) or containing
1% powder with or without 0.5% cholesterol and 0.15% bile acid (ex-
200
WHO monographs on selected medicinal plants
periment 2). Dietary intake of powdered crude drug resulted in a consistent
decrease in serum glucose levels in rats fed cholesterol-free diets, but
not in those fed cholesterol-enriched diets, although no dose–response
was noted. The crude drug had no effect on serum lipid parameters, except
for high-density lipoprotein-cholesterol levels, which were elevated,
indicating an anti-atherogenic activity. In addition, the crude drug caused
a marked reduction of hepatic total cholesterol and triglyceride levels
both in the presence and absence of dietary cholesterol
The effects of a freeze-dried powder of the fruit on serum glucose levelsand lipid parameters of the serum and liver were studied in rats feddiets supplemented with cholesterol and without cholesterol. For 14 days,rats were fed the diets either containing the freeze-dried powder at 0.5, 1or 3% without added dietary cholesterol (experiment 1) or containing1% powder with or without 0.5% cholesterol and 0.15% bile acid (ex-200WHO monographs on selected medicinal plantsperiment 2). Dietary intake of powdered crude drug resulted in a consistentdecrease in serum glucose levels in rats fed cholesterol-free diets, butnot in those fed cholesterol-enriched diets, although no dose–responsewas noted. The crude drug had no effect on serum lipid parameters, exceptfor high-density lipoprotein-cholesterol levels, which were elevated,indicating an anti-atherogenic activity. In addition, the crude drug causeda marked reduction of hepatic total cholesterol and triglyceride levelsboth in the presence and absence of dietary cholesterol
การแปล กรุณารอสักครู่..
