Inhalation: Chronic inhalation nickel dust or fume can cause chronic hypertrophic rhinitis, sinusitis,nasal polyps, perforation of the nasal septum, chronic pulmonary irritation, fibrosis, pulmonary edema, pulmonary eosinophilia,Pneumoconiosis, allergies (asthma-like allergy), and cancer of the nasal sinus cavities, lungs, and possibly other organs