5. Conclusion
The results obtained in this study showed the aqueous crude extract of neem (A. indica) leaves exerted a dose-dependent
Figure 2: Protective effect of aqueous crude extract of neem leaves on renal injury induced by Plasmodium berghei infection in mice. Groups of ICR mice (5 mice of each) were infected with 1 × 107 parasitized erythrocytes of PbANKA by IP injection and given 500, 1,000, and 2,000mg/kg of neem leaf extracts orally for 4 consecutive days. On day 5 of experiment, (a) BUN and (b) creatinine levels were measured and compared to normal and untreated groups. Results were expressed as mean ± SEM. ∗∗