Abstract: Thalassemia is a genetic blood disorder that considered as a major public health problem. It is a challenge
for patients, their families and health care system since it requires a life-long treatment of blood transfusion and
chelating drugs. Aim: This study aimed to explore the needs and concerns of Jordanian mothers who have
thalassemic children. Methods: A qualitative approach was employed to better elucidate the mothers perceptions of
their needs and concerns. Twenty five mothers were recruited purposively from two major thalassemia clinics in The
Ministry of Health in Jordan. Semi-structured, face-to-face interviews were conducted. These interviews were
transcribed verbatim and then translated into English. Data were analyzed using the process of thematic analysis.
Results: The study revealed two major core themes. These themes were: "exaggerated worries and fear", and
"supportive care needs". Participants showed their worries resulting from frequent absenteeism from school, body
image changes, puberty delay, fear of death, and uncertainty about their children’s future. They also expressed their
needs for more information about thalassemia and its treatment, social and professional support, and financial
support. Conclusion: Thalassemia has a significant impact on children and their mothers. A holistic approach should
be used while caring with patients and their families. Nurses and health care professionals are invited to explore the
feelings, concerns and needs of mothers who have thalassemic children and eventually design appropriate care plans
that alleviate their suffering.